Since its inception ZereneX Molecular™ continues to develop and strengthen its global reputation for specializing in the synthesis and supply of rare small molecule compounds to the pharmaceutical and biotech industries.
Brief descriptions of our products are given below.
Further details are available through
above or by contacting our sales team.
The continued use of combinatorial chemistry to generate interesting compounds for high-throughput screening and of parallel synthesis for lead optimisation, has led to the quest for more novel building blocks. At ZereneX Molecular™ we offer a diverse and unique set of over 10,000 (Novel Chemical Entities – NCE™) heterocyclic (small (hetero) cyclic (fused) ring compounds with one or more chemical handles) such as imidazoles, pyridines, pyrazines etc as well as a variety of alycyclic (piperizines, piperidines) and aromatic compounds which are continuously being used to assist medicinal and synthetic chemists globally in developing hit generation and hit-to-lead optimisation libraries.
The compounds are available in multi-gram (1-100 g) quantities (purity 90%min, typically >95%) which make them suitable for high-throughput and combinatorial synthesis or scale-up of lead compounds. The majority of these intermediates are offered ex-stock and we usually aim to despatch them within 48 hours of receiving an order. Where a compound is out of stock we will happily provide an expected delivery date.
Please click here to search our online database of intermediates. Alternatively a copy of our CD which contains structure searchable database in ISIS/Base or SD format can be requested from here.
As well as supplying novel building
blocks we now also offer a range of
unique boronic acids that can be used
in a variety of coupling reactions
i.e. Suzuki coupling, palldium
coupling etc. These compounds
can also be browsed and downloaded from our
Novel compounds used for initial
screening for biological activity is
now available through our
We currently offer 5 novel libraries
each consisting of approx 8000 unique
well as a further library based on
modified natural products. All
of our compounds are available in both
regular plates as well as customer
compounds in our collection are:
- Drug-like, and generally follow Lipinski's
rule of 5
- High quality
libraries are available on our latest CD and can be accessed in both ISIS/Base and
SD format. To request a copy please click
Quality Control and Compound Purity
purity of all compounds are verified by
and or mass spectrometry. Our compounds
have a minimum purity of 90% but we
typically supply intermediates with
purity >95%. 1H-NMR spectra and LC-MS data are available upon
request for all stock compounds.